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“What Even Is a Longevity Clinic?” Why Leaders Are Redrawing the Lines

Longevity clinics have gone from fringe to front-page in just a few years. Now the sector’s own leaders are sounding an alarm. At the 2025 Roundtable of Longevity Clinics, experts warned that everything from hospital programs to hotel spas and dental practices is now calling itself a “longevity clinic,” and that the label is at risk of losing meaning without shared standards (Bensz, 2025; Longevity.Technology, 2025).


At the same time, new research frameworks and a global survey of 82 clinics show how fast this space is professionalising and where the real gaps still are (Cesari et al., 2024; Newman et al., 2025).


Rejuve.AI operates in this context as a health-intelligence partner. The ecosystem is expanding, but it urgently needs common definitions, metrics, and data standards.



1. The Update: Longevity Clinics Are Becoming a Very Broad Category

Coverage from the 3rd Roundtable of Longevity Clinics captures a clear shift. Longevity clinics are no longer a monolith. The term now spans a wide range of models with very different levels of clinical depth and oversight (Bensz, 2025; Longevity.Technology, 2025).


The Modern Longevity Landscape
The Modern Longevity Landscape

1.1 Who Is Now Using the “Longevity Clinic” Label?

Current usage includes:

  • Hospital-embedded healthy longevity clinics 

    Academic centres integrating geroscience with cardiology, endocrinology, mental health, and lifestyle medicine inside public hospitals (Cesari et al., 2024).

  • Private medical longevity centres

    High-touch clinics combining advanced imaging, biomarker panels, and AI-driven risk models for early detection and prevention (Longevity.Technology, 2025).

  • Wellness and spa concepts 

    Hotel-based offerings and retreat models adopting the longevity label with varying degrees of medical oversight (Bensz, 2025).

  • Corporate and hybrid hubs 

    Workplace and office-based longevity offerings positioned as preventive health benefits (Longevity.Technology, 2025).

  • Technology-led providers 

    Digital platforms offering biological age testing, wearable integration, and AI-assisted coaching as a form of “virtual longevity clinic” (Longevity.Technology, 2025).


Joanna Bensz, who convenes the roundtable, warned that growth is coming with a lack of control, making the term “longevity clinic” dangerously elastic unless standards emerge (Bensz, 2025).


1.2 What the Global Survey Tells Us

The Longevity Clinics Survey 2025, based on responses from 82 clinics worldwide, reinforces how heterogeneous the field has become (Newman et al., 2025; Longevity.Technology, 2025):


Longevity Clinics Survey 2025 insights based on responses from 82 clinics worldwide
Longevity Clinics Survey 2025 insights based on responses from 82 clinics worldwide

  • Over 70% of clinics already integrate wearables and digital tools

  • More than 85% assess metabolic, liver, and renal function, but only 37% assess oral health and 22% assess hearing, despite their known links to aging

  • 51% view “pace of aging” as a meaningful marker, but there is no consensus on testing intervals

  • Training in longevity medicine remains inconsistent, with many clinicians calling for shared quality standards

Adoption is high. Ambition is real. Coherence is still emerging (Newman et al., 2025).


2. What Experts Now Think Should Count as a “Healthy Longevity Clinic”

While the market stretches the label, academic and policy work is converging on a more precise definition.

2.1 The Hospital-Based Model

A 2024 open-access framework for establishing healthy longevity clinics in publicly funded hospitals outlines a model that differs sharply from wellness-led offerings (Cesari et al., 2024):


  • Multidisciplinary teams spanning medicine, psychology, nutrition, and allied health

  • Comprehensive functional, clinical, and biomarker-based assessments

  • Evidence-based interventions grounded in geroscience

  • Deep integration with academic research and data sharing


These clinics are explicitly positioned as a counterweight to purely private, consumer-driven models. They are designed to generate best practices that others can adopt (Cesari et al., 2024).


2.2 The Framework for an “Effective” Longevity Clinic

A 2025 framework published in Aging and Disease further defines effective healthy longevity clinics as those that (Bellantuono et al., 2025):

2025 framework published in Aging and Disease on Longevity Clinics
2025 framework published in Aging and Disease on Longevity Clinics

  • Use standardised, transparent biomarkers and biological age measures

  • Operate along clear clinical care pathways

  • Collaborate with research institutions

  • Consider affordability and scalability, not just concierge access


From a research perspective, a longevity clinic is not simply a place selling anti-aging services. It is a clinical environment that systematically targets aging biology and reports outcomes using shared metrics (Bellantuono et al., 2025).


3. Why Leaders Are Pushing “Responsible Longevity”

At the roundtable, Tina Woods framed the current moment as both an opportunity and a significant risk for the sector (Woods, 2025).

3.1 The Case for Standards

Responsible longevity, Woods argued, will depend on (Longevity.Technology, 2025):


  • Shared clinical protocols

  • Common biological age and healthspan metrics

  • Coordinated education for patients, clinicians, and investors


This aligns with the Longevity Clinics Survey’s conclusion that the field is in flux and urgently needs standard-setting initiatives (Newman et al., 2025).


3.2 AI, Empowered Patients, and New Risks

Roundtable participants highlighted how AI and patient behaviour are reshaping clinics (Bensz, 2025):


  • Patients arrive with wearable data, lab panels, and podcast-driven knowledge

  • AI is leading the data revolution, but unsupervised models risk oversimplification

  • Clinical oversight and explainability are essential


These concerns mirror broader ethical perspectives in biogerontology and digital health, which emphasise transparency, explainable AI, and human-in-the-loop decision-making (Parker et al., 2023).


4. Critical Analysis: Where Does This Leave the “Longevity Clinic” Concept?


4.1 The Brand Is Ahead of the Discipline

The term “longevity clinic” is currently used as a broad marketing label, regardless of clinical depth (Longevity.Technology, 2025). Academic work, by contrast, treats healthy longevity clinics as a defined clinical construct with multidisciplinary teams, standardised protocols, and research integration (Cesari et al., 2024).


Without convergence, the risk is clear. “Longevity clinic” becomes the new “anti-aging spa.”


4.2 Clinics as Prototypes for Future Primary Care

Hospital-based longevity clinics offer a model for integrating geroscience-informed care into mainstream healthcare systems (Bellantuono et al., 2025). This integration hinges on several key elements: cross-specialty workflows, standardised biomarker panels, and AI-assisted decision support under clinical governance. If scaled, these comprehensive models have the potential to significantly reshape preventive care.


4.3 Data Is Abundant; Intelligence Is Scarce

The global survey shows high adoption of technology but weak integration with EMRs and standardised protocols (Newman et al., 2025). Many clinics have data but lack shared frameworks to translate it into longitudinal healthspan outcomes.









5. How Rejuve.AI Can Help Define “Responsible Longevity”

Against this backdrop, Rejuve. positions itself as a standard-enabling intelligence layer.

  1. Common metrics 

    Biological age and risk models such as RejuveAge-Q and LinAge2 offer research-anchored alternatives to opaque proprietary scores (Zhavoronkov et al., 2025).

  2. Real-world evidence via IRLDB 

    Longitudinal data capture aligns with academic calls for systematic data contribution (Cesari et al., 2024).

  3. A bridge across clinic types 

    Platforms can support both premium private clinics and public hospital models without fragmenting standards.


6. The Bottom Line for 2026

“Longevity clinic” is currently both more and less than it appears.

  • More, because the best clinics are prototypes for a geroscience-informed care model (Cesari et al., 2024).

  • Less, because the label is applied broadly, risking a repeat of the anti-aging hype cycle (Longevity.Technology, 2025).

The work ahead is not opening more clinics, but defining and measuring what good looks like. That is where Rejuve.ai’s role is clearest. It provides shared metrics, data infrastructure, and explainable AI to turn a marketing-led category into a credible new model of medicine.


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